SCD 700 Clinical Training Course Overview

Development of VTE

SILENT IN NATURE • “Only 25% of patients with DVT display clinical signs” • “Among patients who die from PE, the diagnoses was unsuspected in 70% of them” O’Meara et al. (1990) Prophylaxis for Venous Thromboembolism in Total Hip Arthroplasty. ORTHOPEDICS

Stein, P. and Henry, J. (1995) Prevalence of Acute Pulmonary Embolism Among Patients in a General Hospital and at autopsy. Chest 1995;108;978-981

“...50% of DVT begin intraoperatively, with the highest incidence occurring during surgery and on the first postoperative day, 75% of DVT develop within the first 48 hours after surgery.”

O’Meara et al. (1990) Prophylaxis for Venous Thromboembolism in Total Hip Arthroplasty. ORTHOPEDICS.

A high percentage of thrombi form during surgery…

Nicolaides et al. “A Rational Approach to Prevention” in Nicolaides, A.N., Thromboembolism, Aetiology, Advances in Prevention and management, Medical and Technical Publishing Co. Ltrd. 1975.

PE generally arise from proximal thromboses;

Femoral DVT’s are responsible for 75% of fatal PE

Hill et al. (1997). The Origin of Lower Extremity Deep Vein Thrombi in Acute Venous Thrombosis. American Journal of Surgery. O’Meara et al. (1990) Prophylaxis for Venous Thromboembolism in Total Hip Arthroplasty: A Review. ORTHOPEDICS.

The Nature and Prevalence of VTE

• DVT occurs in over 50% of some categories of hospitalised patients if prophylaxis is not used. •

Prevention of Venous Thromboembolism. Best Practice Guidelines for Australia and New Zealand. 5th Edition

PE remains the most common cause of preventable death; 7% of all deaths in Australian Hospitals are due to PE.

Access Economics. The burden of venous thromboembolism in Australia. The Australia and Zealand Working Party on the Management and Prevention of Venous Thromboembolism. May 2008

VTE (DVT & PE) is likely to cause 5285 preventable deaths in Australia this year and cost the community $1.72 billion.

DVT cost per patient = $116,970 Direct Hospital Cost = $10,000

Access Economics. The burden of venous thromboembolism in Australia. The Australia and Zealand Working Party on the Management and Prevention of Venous Thromboembolism. May 2008.

3.

VTE Causal Factors

WHY DO CLOTS FORM?

Mechanical Prophylaxis for VTE

IMPACTING VIRCHOW’S How the SCD reduces VTE risk

SCD COMPRESSION SYSTEM Clinical

Efficacy

DVT % Risk with NO prophylaxis

DVT % Risk with the combined use of SCD & T.E.D

Stroke – 56%

4.7% - Lacut et al. NEUROLOGY.

THR – 51%

4.6% - Hooker et al. J. of Bone and Joint.

TKR – 47%

5%* - Woolson et al. J. of Orthopaedics. * SCD, T.E.D and Warfarin.

General Surgery – 25%

1% - Scurr et al. Surgery.

Cardiac Surgery – 24%

1.5% PE rate – Ramos et al. CHEST.

KENDALL SCD™ 700 SERIES CONTROLLER AGENDA

New Design Adjustable Bedhook Graphical User Interface Easy Start-Up

Animated Alarm Resolution Improved Durability Reduced Noise

USB Port New Tubing Sleeve Compatibility

KENDALL SCD™ 700 SERIES CONTROLLER NEW DESIGN

The resulting design of the 700 Series satisfies all of these customer requirements Compact Size & Weight

• Size and weight of 700 Serise comparable to the SCD Express controller • Compact and lightweight device, optimal for transportation

Portability & Battery Operation

• Ergonomic handle and battery operation for up to 8 hours, maximizing portability

Kendall SCD™ 700 Series Controller Easy Start-Up

One-touch operation!

KENDALL SCD™ 700 SERIES CONTROLLER ANIMATED ALARM RESOLUTION

• Eighteen (18) alarms in total, categorized three ways:

User Resettable

• Allows user to address alarm and resume operation by pressing A or B button • Eliminates need for power off and on • EXAMPLE: Tubing Disconnect

Manual Reset Required

• User can address alarm • Must then power unit off and on before resuming therapy • EXAMPLE: Vent Alarm • Check for kinked tubing

Service Required

• Indicates component failure that requires BioMed servicing • Icon appears on screen with corresponding alarm code • Facilitates BioMed diagnosis

KENDALL SCD™ 700 SERIES CONTROLLER NEW TUBING

 Tubing Groove Depth Reduced 40%  Easier To Clean Profile  Same Flexibility & Usability

New Tubing Will Replace Current Tubing

KENDALL SCD™ 700 SERIES CONTROLLER SUMMARY OF BENEFITS

New Design Adjustable Bedhook Graphical User Interface Easy Start-Up

Animated Alarm Resolution Improved Durability Reduced Noise

USB Port New Tubing Sleeve Compatibility