ABL90 FLEX Reference Manual Edition D

ABL90 FLEX reference manual

Note to the users of the ABL90 FLEX analyzer Introduction

This note to users outlines the most significant changes and improvements of software version 2.4 in the English version of the ABL90 FLEX reference manual (994-527).

Changes/Description

Brief overview of the change

CHAPTER 3: Calibration

pCO2, cGlu, cLac calibration With the warm start feature in software version 2.4, the last sentence in this section: When a new sensor cassette is installed, the sensitivity calibration is performed more frequently" is not necessarily true and should, therefore, be ignored. The text should, therefore, be as follows: pCO2, cGlu, cLac are sensitivity calibrated on CAL3 and status calibrated on CAL1. For further information on the pCO2, cGlu, cLac calibration, see Calibration of the pCO2 sensor in section pCO2 sensor and Calibration of the metabolite sensors, in section Metabolite sensors in chapter 5 in this manual. pCO2, cGlu, cLac are sensitivity calibrated every four hour and status calibrated with every measurement.

CHAPTER 5: Calibration

Sensitivity, Definition. In the table with the sensitivity range limits, the pO2 max % value has been changed from 105 to 110%.

The sensitivities are range checked: pH

pCO2

pO2

cK+

cNa+

cCa2+

cCl–

cGlu

%

%

%

%

%

%

%

pA/mmol/L pA/mmol/L

Min.

85

60

85

85

85

85

75

100

100

Max.

105

105

110

105

105

105

105

2000

2000

cLac

CHAPTER 7: For ClO4– , interference on cK+ (4 mmol/L level), cCa2+ (1.25 mmol/L level), and cCl (110 mmol/L level) has been detected for test concentration 1.5 mM and the other test concentration levels should be ignored. The new interference results are, thereafter, as follows:

Interference tests

Substance

Perchlorate

Test concentration

1.5 mM

Interference on... cK+ (4 mM level)

cNa+ (140 mM level)

cCa (1.25 mM level)

2+

cCl(105 mM level)

0.3

-

0.27*

4-30

(ClO4-) * Depending on the pH level A "-" indicates that interference has not been measured on the respective parameter.

© 2010 Radiometer Medical ApS. All Rights Reserved. 995-675. 201006A.

Test matrix

Plasma

CHAPTER 10: Conditioning in As a manual conditioning of the sensor cassette pack is not sensor cassette pack possible for the time being, references to this option are no longer not possible valid and, therefore, the following analyzer messages no longer exist in software version 2.4: 972

Sensor conditioning due

1080

Installed sensor cassette was not registered as conditioned

1333

Sensor conditioning started, no BC

1334

Sensor conditioning started, BC

Warm start No. 1340

With the new warm start feature in software version 2.4 the following new analyzer message has been included: Message

Interpretation

Sensor cassette This message is used in the Activity maintenance by log to indicate startup using a sensor Analyzer has cassette which has been left without been interrupted an FTC activity for more than 1 hour.

Operator action No action required

TABLE OF CONTENTS/INDEX: Conditioning in sensor cassette pack not possible

As the pack with the sensor cassette cannot be used for conditioning, the name of the pack has been changed from Conditioning unit to Sensor cassette pack.

Technical documentation

The manual will be updated with the above information as part of the next manual update.

Instructions to user

Please place this note to the users in the binder of your manual.

Table of contents

ABL90 FLEX

Reference manual From software version 2.3

1.

Setup

2.

Disk functions setup programs

3.

Wet section

4.

Electronics

5.

Sensors and measuring technologies

6.

User-defined corrections

7.

Performance characteristics

8.

Parameters

9.

Solutions

10. Analyzer messages I Appendix – Quality control II Appendix – Traceability to primary standards at Radiometer Index Date of issue

System performance The procedures described in this manual must be observed in order to ensure proper system performance, and to avoid hazards. Radiometer cannot provide or verify system performance characteristics if the system is not installed, used and maintained in accordance with Radiometer procedures or if accessories not meeting the specifications provided by Radiometer are used. Radiometer warrants that the data media on which the software included in the system is furnished is free from defects in material and workmanship under normal use for three (3) months from the date of delivery as evidenced by a copy of invoice or receipt.

Third-party software and trademarks The ABL90 FLEX analyzer comprises the Microsoft® Windows®XP Embedded and Sybase® SQL Anywhere® software. By using the system, you accept the terms of the Software License Agreement(s) of the provider(s) of the above software as shown in the End User License Agreement(s) included in the operator's manual. If you cannot accept the terms of the Software License Agreement(s), you should not use the system, but immediately contact your provider for a return of the system and a refund of the purchase price. Microsoft® and Windows® are trademarks of Microsoft Corporation. Sybase® SQL Anywhere® is a trademark of Sybase Incorporated.

Warranties and disclaimer Radiometer makes no warranties, express or implied, other than expressly stated. Any warranties expressly stated in this document are conditional upon the system being installed, used and maintained in accordance with Radiometer procedures, including that only accessories meeting the specifications provided by Radiometer are used. Radiometer disclaims any liability for system performance if the system is not installed, used and maintained in accordance with Radiometer procedures or if accessories not meeting the specifications provided by Radiometer are used. Further, Radiometer disclaims any liability for loss of data and direct, consequential or other damages, including loss of profit or loss of business, whether such claim for damages is based upon contract, negligence or tort (including strict liability), and even if Radiometer has knowledge of the possibility of the potential damage or loss.

Confidentiality The contents of this document shall not be reproduced or communicated to any third party without the prior written consent of Radiometer.

Changes This document is subject to change without notice and you are urged to contact Radiometer to verify whether the document has been changed. While every effort is made to ensure the correctness of the information provided in this document as changed from time to time, Radiometer disclaims any liability for errors and omissions.

Radiometer, the Radiometer logo, ABL, AQT, TCM, RADIANCE, PICO and CLINITUBES are trademarks of Radiometer Medical ApS. © 2010 Radiometer Medical ApS. All rights reserved.

ABL90 FLEX reference manual

Contents

Contents 1. Setup ... 1-1 Setup menu structure ... 1-3 Analyzer security ... 1-4 Programs... 1-4 General security ... 1-4 Operators and passwords... 1-5 Access profiles ... 1-8 Analysis setup ...1-10 Program ...1-10 Syringe/capillary modes...1-10 Setting up a new measuring mode ...1-11 Selecting a parameter profile...1-11 Disabled versus deselected parameter ...1-11 Editing name of button ...1-11 Selecting a default layout...1-12 Reference ranges and critical limits...1-12 Selecting sample type ...1-12 Selecting sex ...1-12 Setting age group limits...1-13 Setting reference and critical limits for each parameter ...1-14 Reportable ranges ...1-15 Patient report setup...1-16 Program ...1-16 Creating a layout ...1-16 Editing a layout ...1-17 Patient ID layout ...1-17 Default values ...1-18 Editing patient result layout ...1-19 Sample pre-registration setup...1-20 Sample age evaluation setup ...1-21 Calibration schedule setup...1-22 Program ...1-22 Editing the settings ...1-22 Available calibration schedule options ...1-22 Quality control setup ...1-23 Program ...1-23 Manual quality control (QC) solutions ...1-23 Quality control schedule setup ...1-24 QC ranges...1-26 QC input setup ...1-28 QC statistics ...1-29 Westgard Rules setup ...1-30 Reference ...1-32 RiLiBÄK ranges ...1-32 Replacement setup...1-35 Program ...1-35 Replacement schedule setup...1-35 Recommended replacement intervals...1-36

Contents

ABL90 FLEX reference manual

User activities...1-37 Adding a user activity...1-37 Editing a user activity...1-38 Deleting a user activity ...1-38 Maintenance planning ...1-39 Replacement warnings ...1-40 Parameters and input setup ...1-41 Program ...1-41 Parameter setup ...1-41 Units setup ...1-43 User-defined patient data items ...1-44 User-defined notes ...1-46 Analyzer settings ...1-47 Program ...1-47 Analyzer identification ...1-47 Time/date setup ...1-48 Acoustic signal setup ...1-49 Barometer setup ...1-50 Languages ...1-51 Communications setup...1-52 Program ...1-52 RADIANCE connection setup ...1-52 LIS/HIS connection setup ...1-53 Automatic data transmission setup ...1-55 Automatic data request setup ...1-57 Patient lookup setup ...1-58 QA Portal connection setup...1-59 Disk functions setup ...1-60 Program ...1-60 Automatic archiving setup ...1-60 Automatic backup setup ...1-62 Printers ...1-63 Program ...1-63 Printer setup ...1-63 Automatic printing ...1-64 Corrective actions ...1-65 Program ...1-65 Conditions and corrective actions ...1-65 Explanation of corrective actions ...1-66 Miscellaneous setup...1-67 Program ...1-67 List of options ...1-67 Activating/ deactivating an option ...1-68 Selecting HbF correction ...1-68 Analyzer messages ...1-69 Setting the time for the screen saver to appear...1-69 Setup default settings...1-70

ABL90 FLEX reference manual

Contents

Access to Radiometer default setup ...1-70 Operators and passwords...1-70 Analysis setup ...1-71 Calibration schedule ...1-72 Quality control setup ...1-72 Replacement setup ...1-73 General setup ...1-73 Setups without Radiometer settings ...1-77 Print setup ...1-78 Contents of setup settings ...1-79 Groups of setup settings ...1-79 Parameters group ...1-79 General group ...1-80 Schedules, etc...1-81 Interfacing facilities ...1-82 Connecting a mouse...1-82 Connecting an alpha-numeric keyboard...1-82 Connecting to a network ...1-82 External barcode reader...1-83 Sample counter ...1-84 Purpose...1-84 Description ...1-84 2. Disk functions setup programs... 2-1 General information... 2-2 Disk functions programs ... 2-2 Definitions ... 2-2 Data storage options ... 2-2 Disk handling rules ... 2-2 Creating a WDC report... 2-3 Purpose... 2-3 Backing up all data... 2-4 Purpose... 2-4 Restoring all data... 2-6 Purpose... 2-6 Exporting data logs ... 2-7 Purpose... 2-7 Importing/exporting archives... 2-8 Purpose... 2-8 Exporting an archive ... 2-8 Importing an archive... 2-8 Deleting an archive ... 2-8 Saving setup ... 2-9 Purpose... 2-9 Loading/restoring setup ...2-10 Purpose...2-10 3. Wet section ... 3-1 Introduction ... 3-2 Definition ... 3-2 Contents of wet section ... 3-2 Wet section diagram... 3-3 Diagram ... 3-3 Measuring processes ... 3-4 Introduction... 3-4 General information... 3-4

Contents

ABL90 FLEX reference manual

Prior to measurement... 3-4 Heating ... 3-4 Solutions ... 3-4 Waste removal ... 3-4 Patient samples ... 3-5 Measuring process ... 3-5 Rinse process ... 3-6 Calibration ... 3-7 pO2 calibration ... 3-7 pCO2, cGlu, cLac calibration ... 3-7 pH, cK+, cNa+, cCa2+, cCl– calibration ... 3-7 Oxi calibration ... 3-7 Automatic QC ... 3-8 Measuring process ... 3-8 Manual QC samples ... 3-9 Measuring process ... 3-9 4. Electronics ... 4-1 General information... 4-2 General information... 4-2 General information ... 4-2 Communication ... 4-2 Electronic boards and components... 4-3 Power supply ... 4-3 Sensor Module ... 4-3 Inlet positioning ... 4-3 User Interface Module ... 4-3 Printer unit ... 4-4 Sample mixer (for safePICO only) ... 4-4 5. Sensors and measuring technologies ... 5-1 Overview ... 5-2 General construction ... 5-2 Sensors... 5-2 General measuring principles ... 5-3 Introduction... 5-3 Activity vs. concentration... 5-3 Conversion of activity to concentration... 5-3 Calibration ... 5-4 General information... 5-5 Definition ... 5-5 Frequency ... 5-5 Calibration solutions... 5-5 Traceability of calibration solutions... 5-5 The calibration equation... 5-6 Definition ... 5-6 Use... 5-6 Deriving the calibration line... 5-6 Scale ... 5-6 Sensitivity... 5-7 Definition ... 5-7 Updating ... 5-7 Sensitivity ... 5-7 Status... 5-7 Drift... 5-7 Measurement ... 5-8

ABL90 FLEX reference manual

Contents

Sample measurements ... 5-8 Corrections ... 5-8 Quality Management... 5-9 Introduction... 5-9 System/ analysis checks ... 5-9 Calibration ...5-12 Measurement ...5-12 Reference electrode...5-13 Background information about the reference electrode ...5-14 Purpose...5-14 Fixed potential ...5-14 Use...5-14 Construction of the reference electrode ...5-15 Diagram ...5-15 Parts and functions ...5-15 pH and electrolyte sensors ...5-16 Construction of the pH and electrolyte sensors ...5-17 Diagram ...5-17 Parts and description...5-17 Measuring principle of the pH and electrolyte sensors ...5-18 Potentiometric measuring principle...5-18 Electrode chain...5-18 Parts and description...5-18 Electrode chain potential...5-18 Unknown potential ...5-19 Ion-sensitive membrane ...5-19 Nernst equation...5-19 Activity and concentration...5-19 Calibration of the pH and electrolyte sensors...5-20 Introduction...5-20 2-point calibration ...5-20 Calibration levels ...5-20 Calibration ...5-20 Measurement – pH and electrolytes ...5-21 Measurement ...5-21 Checks ...5-21 pCO2 sensor ...5-22 Construction of the pCO2 sensor...5-23 Diagram ...5-23 Parts and description...5-23 Measuring principle of the pCO2 sensor ...5-24 Electrode chain...5-24 Parts and description...5-24 Electrode chain potential...5-24 Measuring process ...5-25 Calibration of the pCO2 sensor ...5-26 Introduction...5-26 Calibration levels ...5-26 Sensitivity ...5-26 Measurement – pCO2 ...5-27 Measurement ...5-27 Checks ...5-27 pO2 sensor ...5-28 Measuring principle of the pO2 sensor ...5-29 Optical system for pO2 ...5-29

Contents

ABL90 FLEX reference manual

Measuring sequence...5-29 Calculations ...5-29 Calibration of the pO2 sensor ...5-30 Introduction...5-30 Sensitivity ...5-30 Status...5-30 Measurement - pO2 ...5-31 Checks ...5-31 Metabolite sensors ...5-32 Construction of the metabolite sensors...5-33 Basic description...5-33 Diagram ...5-33 Parts and description...5-33 Zero current ...5-33 Calibration of the metabolite sensors ...5-34 Sensitivity ...5-34 Measurement – metabolites...5-35 Measurement ...5-35 Checks ...5-35 Measuring principle of the metabolite sensors ...5-36 Amperometric measuring principle ...5-36 Electrode chain...5-36 Parts and functions ...5-36 Measuring process ...5-37

ctHb and derivates ...5-38 General information...5-39 Measured parameters...5-39 Construction ...5-39 Measurement cycle ...5-40 Lambert-Beer's law ...5-40 Absorbance...5-41 Total absorbance ...5-41 Continuous spectrum ...5-41 Spectrum examples ...5-42 Determining concentrations...5-42 Matrix of constants ...5-43 Calibration of the optical system ...5-44 Calibration materials ...5-44 Zero point ...5-44 Cuvette path length ...5-44 tHb calibration frequency ...5-44 Correcting for interferences ...5-45 HbF versus HbA...5-45 Deviation of results ...5-45 Detecting HbF ...5-45 Correcting for HbF ...5-45 Repressing spectra...5-45 Residual spectrum ...5-46 Measurement and corrections ...5-47 Oximetry parameters ...5-47 Bilirubin ...5-47 Restrictions...5-48 Corrections for ctHb ...5-49 Corrections for ctBil ...5-49 References ...5-50 6. User-defined corrections ... 6-1

ABL90 FLEX reference manual

Contents

General information... 6-2 Purpose of use ... 6-2 User-defined corrections ... 6-2 Preparatory action ... 6-2 Entering user-defined corrections ... 6-3 Correction factors for pH and blood gases ... 6-4 Correcting slope and offset... 6-4 Correction factors for oximetry parameters ... 6-5 Allowed corrections ... 6-5 ctHb ... 6-5 sO2 ... 6-5 FCOHb ... 6-6 FMetHb ... 6-6 FHbF... 6-6 FO2Hb and FHHb... 6-6 ctBil... 6-7 Correction factors for electrolyte and metabolite parameters ... 6-8 Correcting slope and offset... 6-8 Resetting corrections to default values ... 6-8 7. Performance characteristics... 7-1 General information... 7-2 Definition of terms ... 7-3 Bias ... 7-3 Reference methods ... 7-3 Coefficient of variation (CV%) ... 7-5 Confidence intervals... 7-5 Repeatability/Reproducibility ... 7-5 Total analytical error ... 7-5 Test conditions ... 7-6 Performance test results – chart description... 7-7 Modes ... 7-7 Number of measurements ... 7-7 Performance test results – pH ... 7-8 Reference method... 7-8 BiasPrim.ref ... 7-8 BiasSec.ref and Repeatability – blood samples ... 7-8 Performance test results – pCO2 ... 7-8 Reference method... 7-8 BiasPrim.ref and Repeatability – blood samples... 7-8 Performance test results – pO2 ... 7-9 Reference method... 7-9 BiasPrim.ref and Repeatability – blood samples... 7-9 Performance test results – cK+ ... 7-9 Reference method... 7-9 BiasPrim.ref ... 7-9 BiasSec.ref and Repeatability – blood samples ... 7-9 Performance test results – cNa+ ...7-10 Reference method...7-10 BiasPrim.ref and Repeatability – blood samples...7-10 Performance test results – cCl– ...7-10 Reference method...7-10 BiasPrim.ref ...7-10 BiasSec.ref and Repeatability – blood samples ...7-10 Performance test results – cCa2+ ...7-11 Reference method...7-11

Contents

ABL90 FLEX reference manual

BiasPrim.ref ...7-11 BiasSec.ref and Repeatability – blood samples ...7-11 Performance test results – cGlu...7-11 Reference method...7-11 BiasPrim.ref and Repeatability – blood samples...7-11 Performance test results – cLac...7-12 Reference method...7-12 BiasPrim.ref and Repeatability – blood samples...7-12 Performance test results – ctHb ...7-13 Reference method...7-13 BiasPrim.ref and Repeatability – blood samples...7-13 Performance test results – sO2 ...7-14 Reference method...7-14 BiasPrim.ref ...7-14 BiasSec.ref and Repeatability – blood samples ...7-14 Performance test results – FO2Hb ...7-15 Reference method...7-15 BiasSec.ref and Repeatability – blood samples ...7-15 Performance test results – FCOHb ...7-15 Reference method...7-15 BiasPrim.ref ...7-15 BiasSec.ref and Repeatability – blood samples ...7-16 Performance test results – FMetHb ...7-16 Reference method...7-16 BiasPrim.ref ...7-16 BiasSec.ref and Repeatability – blood samples ...7-16 Performance test results – FHHb ...7-17 Reference method...7-17 BiasSec.ref and Repeatability – blood samples ...7-17 Performance test results – FHbF ...7-17 Reference method...7-17 BiasPrim.ref and Repeatability – blood samples...7-17 Performance test results – bilirubin...7-18 Reference method...7-18 BiasPrim.ref ...7-18 BiasSec.ref ...7-18 External test results ...7-18 Interference tests ...7-20 pH/blood gas ...7-20 Electrolytes...7-21 Metabolites ...7-23 Oximetry parameters ...7-25 FHbF sensitivity for pH changes ...7-26 ctBil sensitivity for MCHC variations...7-26 Anticoagulants (sampling)...7-28 List of references ...7-29 8. Parameters ... 8-1 General information... 8-2 The Deep Picture ... 8-2 Symbols ... 8-3 Ranges and limits ... 8-4 Derived parameters ... 8-4 Measured parameters... 8-5 Sample type ... 8-5 Units... 8-5 Default values ... 8-5

ABL90 FLEX reference manual

Contents

Measured parameters ... 8-6 General information ... 8-6 pH ... 8-6 cH+ ... 8-6 pCO2 ... 8-6 pO2... 8-7 Baro ... 8-7 ctHb ... 8-7 sO2 ... 8-8 FO2Hb ... 8-8 FCOHb ... 8-8 FMetHb ... 8-8 FHHb ... 8-9 FHbF... 8-9 cK+ ... 8-9 cNa+ ... 8-9 cCa2+ ... 8-9 cCl- ...8-10 cGlu...8-10 cLac...8-10 ctBil...8-10 Input parameters ...8-13 Definition ...8-13 T ...8-13 FO2(I) ...8-13 ctHb ...8-13 RQ...8-13 – pO2(v ) ...8-13 – sO2(v ) ...8-14 · Q t ...8-14 · VO2 ...8-14 VCO...8-14 FCOHb(1) ...8-14 FCOHb(2) ...8-14 Derived parameters...8-15 General information ...8-15 Acid-base derived parameters ...8-15 Oximetry derived parameters ...8-16 Oxygen derived parameters ...8-16 Units and numerical format of derived parameters ...8-19 Calculated versus estimated parameters ...8-19 Electrolyte parameters ...8-19 Possible ranges and precision (number of decimals)...8-20 List of equations ...8-23 Units and symbols ...8-23 pH(T)...8-23 cH+(T) ...8-23 pCO2(T)...8-23 cHCO3–(P)...8-23 cBase(B) ...8-24 cBase(B,ox) ...8-24 cBase(Ecf) ...8-24 cBase(Ecf,ox)...8-24 cHCO3–(P,st) ...8-24 ctCO2(P)...8-24 ctCO2(B)...8-25 pH(st) ...8-25 Hct ...8-25 pO2(T) ...8-25

Contents

ABL90 FLEX reference manual

pO2(A) ...8-26 pO2(A,T)...8-26 pO2(a)/FO2(I)...8-26 pO2(a,T)/ FO2(I) ...8-27 p50 ...8-27 p50(T) ...8-27 p50(st) ...8-28 pO2(A-a) ...8-28 pO2(A-a,T)...8-28 pO2(a/A) ...8-28 pO2(a/A,T)...8-28 (or px)...8-29 ctO2 ...8-29 – ctO2(av ) ...8-29 BO2 ...8-29 ctO2(x) (or cx) ...8-30 · D O2 ...8-30 · Q t ...8-30 · VO2 ...8-30 FShunt ...8-31 FShunt(T)...8-32 RI...8-32 RI(T) ...8-32 Qx ...8-33 sO2 ...8-33 FO2Hb ...8-33 FHHb ...8-34 V(B) ...8-34 Anion Gap,K+ ...8-34 Anion Gap ...8-34 cCa2+(7.4) ...8-34 Eq. 46-47 ...8-34 mOsm...8-34 FHbF...8-34 pO2(x,T) ...8-35 VCO2/V(dry air) ...8-36 VO2/V(dry air) ...8-36 Oxyhemoglobin dissociation curve (ODC)...8-37 ODC equations ...8-37 The ODC reference position ...8-37 The ODC displacement ...8-38 The actual ODC position...8-39 Determining the actual displacement ...8-39 Coordinates on the ODC ...8-41 Conversion of units ...8-42 SI units ...8-42 Temperature ...8-42 cK+, cNa+, cCl– ...8-42 cCa2+ ...8-42 Pressure ...8-42 ctHb ...8-42 – ctCO2, ctO2, ctO2(av ), BO2 ...8-42 ·

VO2 ...8-42 cGlu...8-43 cLac...8-43 ctBil...8-43 Default values ...8-44 Values...8-44 References ...8-45

ABL90 FLEX reference manual

Contents

9. Solutions ... 9-1 General information... 9-2 Introduction... 9-2 Solution pack ... 9-2 Lot ... 9-2 In vitro diagnostic use ... 9-2 Expiration date... 9-2 Storage ... 9-2 Material safety Data Sheets... 9-2 Solutions ... 9-3 Use... 9-3 Pouch volume ... 9-3 Composition... 9-3 Certificate of traceability ... 9-5 10. Messages ... 10-1 List of analyzer messages...10-2 Messages on user and manager levels ...10-2 I

Appendix - Quality control... I-1 General information... I-2 Statistical parameters... I-3 Control ranges (for manual QC only)... I-4 About control ranges ... I-4 Definitions ... I-4 User control ranges (for manual QC only) ... I-6 Introduction... I-6 Establishing analyzer-specific control ranges... I-6 Table 1: ... I-7 Statistics factor and statistics range... I-9 Definitions ... I-9 Example ... I-9 Temperature corrections (for manual QC only) ... I-10 Purpose... I-10 Parameters that require temperature correction ... I-10 Temperature corrections for pH, pCO2 and pO2 ... I-11 Westgard rules ... I-12 About Westgard rules ... I-12 Plot lines ... I-12 Rule 12s ... I-13 Rule 13s ... I-13 Rule 22s ... I-13 Rule R4s ... I-14 41s ... I-14 Rule 10x ... I-14 Quality control evaluation... I-15 Evaluation procedure... I-15

II Appendix - Traceability to the primary standards at Radiometer ...II-1 Introduction ... II-2 Traceability ... II-3 pH ... II-3 pCO2 and pO2 ... II-3 cK+ and cNa+ ... II-3 cCa2+ ... II-4 cCl– ... II-4 cGlu... II-4

Contents

ABL90 FLEX reference manual

cLac... II-4 ctHb ... II-4 Saturation – sO2 = 100 %... II-5 Saturation – sO2 = 0 % ... II-5 FCOHb – normal value... II-5 FCOHb – 100 %... II-5 FMetHb ... II-5 FHbF... II-5 Hct ... II-5 ctBil... II-6 References ... II-7

Index Date of issue

1. Setup Setup menu structure ... 1-3 Analyzer security... 1-4 Analysis setup...1-10 Syringe modes ...1-10 Reference ranges and critical limits...1-12 Reportable ranges...1-15 Patient report setup ...1-16 Sample pre-registration setup...1-20 Sample age evaluation setup ...1-21 Calibration schedule setup ...1-22 Quality control setup...1-23 Manual quality control (QC) solutions ...1-23 Quality control schedule setup ...1-24 QC ranges...1-26 QC input setup ...1-28 QC statistics...1-29 Westgard Rules setup ...1-30 RiLiBÄK ranges ...1-32 Replacement setup ...1-35 Replacement schedule setup...1-35 User activities...1-37 Maintenance planning ...1-39 Replacement warnings...1-40 Parameters and input setup ...1-41 Parameter setup ...1-41 Units setup ...1-43 User-defined patient data items ...1-44 User-defined notes ...1-46 Analyzer settings...1-47 Analyzer identification ...1-47 Time/date setup ...1-48 Acoustic signal setup ...1-49 Barometer setup ...1-50 Languages ...1-51 Communications setup ...1-52 RADIANCE connection setup ...1-52 LIS/HIS connection setup...1-53 Automatic data transmission setup ...1-55

1-1

1. Setup

ABL90 FLEX reference manual

Automatic data request setup ...1-57 Patient lookup setup...1-58 QA Portal connection setup...1-59 Disk functions setup...1-60 Automatic archiving setup ...1-60 Automatic backup setup...1-62 Printers...1-63 Printer setup ...1-63 Automatic printing ...1-64 Corrective actions...1-65 Miscellaneous setup ...1-67 Setup default settings ...1-70 Print setup ...1-78 Contents of setup settings ...1-79 Interfacing facilities ...1-82 Sample counter...1-84

1-2